ABSTRACT
Isolated pancreatic metastases of clear cell renal carcinoma are rare. Clear cell renal carcinoma (CCRC) is responsible for approximately 20-30 % of cases that present metastases at diagnosis. Despite that pancreatic involvement is inusual, this is an organ were particularly and frequently place as the only dissemination site. The aim of this report was to evaluate the surgical and oncological results of patients submitted to pancreatectomy consecutively to a CCRC. Patients with pancreatectomy because of metastases were selected in a 10 -year period. Clear cell renal carcinoma spreads both by direct perinephric extension and by hematogenous and lymphatic routed. The treatment of localized CCRC is surgical. For patients with metastatic CCRC, no efficacious agent has ever been identified, and there is no standard or accepted therapy. The results of this study are presented and discussed